For every illness, there is a medicine to treat it
We all take these medicines as doctors prescribed for the illness
It helps in easing the symptoms or curing the illness
We know about these all,
but we don’t know exactly how these medicines do their job in our body
That is what we are learning today
How a medicine process in our body and helps us?
After we take a pain killer for a shoulder pain
At first, it enters into our digestive system
Where the first process begins
If first dissolves in our digestive system
After it dissolved, it enters into the small intestine which helps it get into the bloodstream
The small intestine walls are which helps in this process,
they absorb the dissolved substance and releases it into the bloodstream
Then it enters into the network of blood vessels
These blood vessels take this into a vein
From which the blood and dissolved material in it are taken to the lever
Then the process continues in the lever
Now the blood and drug molecules enter into the lever blood vessels
The lever enzymes react with the pain killer molecules
Then some of these molecules are neutralized with this chemical reaction
That means here the molecules are metabolized and form into metabolites
These metabolites do not work as pain killers
Some of the molecules are managed to escape from this neutralization and
Goes into veins and enters the body’s circulatory system
After we take it takes about 30 minutes for a pill to enter our circulatory system
When it enters into the circulatory system it passes throughout the body including organs
Heart, kidneys, brain and again through the lever
During there circulation through the system,
They enter the specific part where our body has full pain response
Then they bind to the molecules there, which are responsible for that reaction
Then these molecules stop the production of compounds which releases the pain signals
As more molecules accumulate the more painkilling effect increases
This pain-killing effect reaches its maximum of about 1 or 2 hours after we take the pill
After that our body starts the elimination process of the drug
The dose of the molecules starts to decrease in the blood
For every to hours it becomes half
It’s because as many times it is going into the liver
Each time some of the molecules become metabolites
At last, all the molecules metabolites and comes out the body
It comes out of the body through filtration in kidneys
Then the accumulated molecules at the pain response site also carried out by the blood
When that molecule carried out if the cause of the pain heals then you didn’t feel the pain
If it didn’t heal then you feel pain again
Then you have to take another pill
That is the reason why some drugs are prescribed two to three times a day
This process is the same for all the medicines
But the release of molecules metabolizing of them varies
Based on the type of drug, amount of dose, type of person
As when the medicine is given as an injection other than oral
It skips the first step of dissolving and entering the bloodstream
It directly enters into the bloodstream and started circulating in the system
Taking at the right doses is more important than the type of medicine
If the dose is too low then it doesn’t do the right job
As it releases fewer molecules and they all are metabolised in the liver in the first process of circulation
So they didn’t reach the target zone for the work
If the dose is too high then the molecules releases at a high rate
And these molecules are too much in the stream
Enters all the organs and organs work increases
That means it puts so much pressure on the organs
That means it is dangerous to the organs
These are the reasons why we should take the medicines at the right dose
otherwise, it may lead to organ problems
And it is more important to give the right dose of medicines to children
Because in childhood the enzymes in the liver are very low
So metabolizing of drugs is too low
That is the reason why medicines for children vary and are at very low doses
Along with that, there are also some other factors which can affect the process of medicine
They are
DNA
Every person has a unique DNA and unique reaction to medicine
Age
As we age our ability to process medicine too changes
Diet
Our diet also plays a role in our ability to process medicine
Disease
Each disease deals with medicine uniquely
Pregnancy
Ability to process medicine changes a lot during pregnancy
Then how can we know what is the best dose for us
Some medicines show the dose on the label
It may help but they are tested on a low number of people
So you have only one option to take the right dose of medicine
Consulting your Doctor or Pharmacist
Your doctor gives the medicines with small doses and eventually increases if it is not effective
So always consult your doctor for the best suggestions about the drugs
This is the journey of a drug inside our body
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